Integrin beta 3 Antikörper

Produktnummer ABIN965812

Dieser Maus Monoklonal Antikörper erkennt spezifisch Integrin beta 3 in FACS, IHC (fro) und IHC (p). Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für Integrin beta 3 Antikörper (ABIN965812)

Target: Integrin beta 3 (ITGB3)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Integrin beta 3 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: Y2-51

Produktdetails anti-Integrin beta 3 Antikörper

Aufreinigung: Concentrated.

Immunogen: Phytohemagglutinin-stimulated Human Mononuclear Cells

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry: (Paraffin/Frozen (acetone fixed)) 1:50-1:100, FLOW.
Staining Procedure: Prolonged fixation in buffered formalin can destroy the epitope. The antibody may be used at a dilution of 1:50 -1:100 in IHC. When using paraffin-embedded and formalin-fixed tissues, enzymatic predigestion is required. The optimal conditions should be determined by the individual laboratory.

Kommentare:

Cellular Localization: Cell Membrane.
Recommended Positive Control: Lymphoid Tissues

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/ml.

Buffer: 20 mM Tris-Borate, 150 mM Sodium Chloride, dialyzed media RPMI 1640/D-MEM containing Fetal Bovine Serum, BMC-6 Carrier Polysaccharides, Carrier Protein, pH 7.5

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-Integrin beta 3 Antikörper (ABIN965812)

Ford-Hutchinson: "Regulation of leukotriene biosynthesis." in: Cancer metastasis reviews, Vol. 13, Issue 3-4, pp. 257-67, (1995) (PubMed).

Details zu Integrin beta 3

Target: Integrin beta 3 (ITGB3)

Andere Bezeichnung: CD61, Platelet Glycoprotein IIIa

Hintergrund: This antibody reacts with platelet glycoprotein IIIa, a 110 kD glycoprotein present on human platelets and megakaryocytic progenitors. This antibody reacts with platelets, megakaryocytes, megakaryoblasts, endothelium, and osteoclasts.

Gen-ID: 3690

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex